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Search Results for " jnk3 inhibitor-3 "

6

Compounds

Cat No. Product Name Synonyms Targets
T72714 JNK3 inhibitor-3 JNK
JNK3 Inhibitor-3 (compound 15g) is a selective, blood-brain barrier permeable, and orally active inhibitor of c-Jun N-terminal kinase 3 (JNK3) with IC50 values of 147.8 nM, 44.0 nM, and 4.1 nM against JNK1, JNK2, and JNK...
T40248 JNK3 inhibitor-1 JNK3 inhibitor-1
JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 μM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent...
T8477 IQ-3 JNK
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...
T3598 JNK-IN-7 JNK inhibitor JNK
JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.
T11702 J30-8 Others
J30-8, a potent and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitor with an IC50 of 40 nM and 2500-fold isoform selectivity against JNK1α1 and JNK2α2, exhibits neuroprotective activity in vitro and shows pro...
T79754 JNK-IN-14 JNK
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits be...
TargetMol